Rome, ItalyThe world's most famous fountain — Nicola Salvi's 1762 Baroque masterpiece at the terminus of one of Rome's ancient aqueducts. Visit at 5am to see it empty; by 10am the crowds make coin-throwing impossible. The fountain collects €3,000 daily, donated to charity.
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The greatest monument of the ancient world — a 2,000-year-old amphitheatre that held 50,000 spectators for gladiatorial combat. Book timed entry tickets online weeks in advance to avoid the enormous queues; the arena floor access and underground tunnels are worth the premium ticket.
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The world's greatest single art collection — 54 galleries of ancient sculptures, Renaissance paintings, and Raphael's Rooms leading to Michelangelo's Sistine Chapel ceiling. Allow 4 hours minimum; book timed entry weeks ahead. The early morning tours (before public opening) offer an unforgettable silent viewing.
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The best-preserved building of ancient Rome — a 125 AD domed temple converted to a church, with a 43-meter concrete dome that remained the world's largest for 1,300 years. The oculus (open hole at the dome's apex) lets in rain, which drains through the ancient floor. Extraordinary.